In conclusion, the results of this paper indicate that the antifungal activity of the P. amurense extract against C. albicans is due to multiple effects, including inhibiting biofilm formation, damaging the cell membranes, reducing the cell adhesion to polystyrene surfaces and fungicidal activity. The findings indicate that the P. amurense extract holds a great promise for use in the treatment of biofilm-associated Candida infection and further purification is required to obtain potential antifungal compounds.