본문 바로가기 보조메뉴바로가기 대메뉴 바로가기

No.1 for Student Experience Semyung Univ.

본문 시작

논문집 검색

논문 관리

논문제목

Protein array analysis of cytokine levels on the action of Angelicae Dahuricae Radix on macrophage RAW cells and peripheral blood mononuclear cells (PBMC)

-

요약본

1. Protein array analysis of cytokine levels on the macrophage RAW cells - The results of protein array on RAW 264.7 cell line shows that GCSF, IL-6, MCP-1, RANTES, and TNF-a were increased relatively on BJ treated (Table 1 and Figure 1). The GCSF expressions of control and BJ treated (100 and 10 ug/ml) were 3.83 ± 0.10, 6.66 ± 0.57, and 5.51 ± 0.17. The IL-6 expressions of control and BJ treated (100 and 10 ug/ml) were 3.05 ± 0.03, 7.28 ± 0.29, and 3.91 ± 0.90. The MCP-1 expressions of control and BJ treated (100 and 10 ug/ml) were 3.85 ± 0.04, 8.27 ± 0.01, and 7.58 ± 0.24. The RANTES expressions of control and BJ treated (100 and 10 ug/ml) were 3.76 ± 0.00, 5.73 ± 0.77, and 4.19 ± 0.11. The TNF-a expressions of control and BJ treated (100 and 10 ug/ml) were 3.77 ± 0.15, 9.88 ± 0.02, and 7.94 ± 0.16 (Figure 2). 2. Protein array analysis of cytokine levels on the PBMC - The results of protein array on PBMC shows that GRO, GRO-a, IL-5, IL-6, IL-10, MCP-1, RANTES, and TNF-a were increased relatively on BJ treated (Table 2 and Figure 3). The GRO expressions of control and BJ treated (100 and 10 ug/ml) were 1.29 ± 0.06, 8.78 ± 0.27, and 9.45 ± 0.53. The GRO-a expressions of control and BJ treated (100 and 10 ug/ml) were 1.40 ± 0.25, 1.81 ± 0.07, and 3.39 ± 0.41. The IL-5 expressions of control and BJ treated (100 and 10 ug/ml) were 1.40 ± 0.07, 6.72 ± 0.00, and 3.74 ± 0.39. The IL-6 expressions of control and BJ treated (100 and 10 ug/ml) were 1.60 ± 0.03, 1.45 ± 0.14, and 3.85 ± 0.27. The IL-10 expressions of control and BJ treated (100 and 10 ug/ml) were 1.80 ± 0.25, 4.72 ± 0.15, and 5.04 ± 0.95. The MCP-1 expressions of control and BJ treated (100 and 10 ug/ml) were 1.49 ± 0.29, 1.94 ± 0.52, and 2.84 ± 1.05. The RANTES expressions of control and BJ treated (100 and 10 ug/ml) were 1.50 ± 0.05, 4.33 ± 1.08, and 6.01 ± 0.05. The TNF-a expressions of control and BJ treated (100 and 10 ug/ml) were 1.40 ± 0.40, 9.14 ± 0.30, and 7.12 ± 0.50 (Figure 4).
  • 게재일 2006년 12월 31일
  • 저자 길종섭
  • 공동저자 김명규, 이세나, 박해정, 정주호, 부영민, 김선여, 김호철, 임강현
  • 연구소 구분 IS04
  • 학술지명/세미나명 한의학연구소논문집
  • 출판사명/주최기관 한의학연구소
  • 권호 9
  • 페이지 수 10
  • 출력여부 Y

목록

  • 담당부서 : 한의학연구소
  • 담당자 : 전인숙
  • 연락처 : 043-649-1870
  • 최종수정일 : 2024-10-26
만족도조사
만족도 조사 이 페이지에서 제공하는 정보에 대하여 만족하시나요?